Chandan K. Sen, PhD
College of Medicine
Molecular Carcinogenesis and Chemoprevention
Wounds and Injuries, Cancer, Oxidative stress, Anoxia, Ischemia, stroke, Inflammation, Hyperoxia
Dr. Sen’s program is interested in tissue injury and repair and works across three organ systems- skin, brain and heart. His group is interested in miRNA biology, redox signaling and tissue oxygenation. In the skin, the Sen group works on wound healing – both experimental as well as clinical. In the brain, specific focus is directed towards stroke biology and related neurodegeneration. The Sen group has identified the alpha-tocotrienol form of vitamin E as a major protector against stroke-induced injury to the brain. In the heart, emphasis is on post-infarction myocardial remodeling with emphasis on miRNA biology. Across all of the above programs, the Sen groups uses advanced MRI, echocardiographic as well hyperspectral imaging approaches.