Kalpana Ghoshal, PhD
College of Medicine
Carcinoma, Hepatocellular, Liver Cancer, Lymphoma, Non-Hodgkin, Cancer, Liver Cancer, Experimental, Choline Deficiency, Fatty Liver, Disease Models, Animal, Folic Acid Deficiency, Cell Transformation, Neoplastic
Dr. Goshal’s lab focuses on elucidating the functions of microRNAs and the factors involved in DNA methylation / hydroxymethylation in liver biology and the consequence of their deregulation in liver disease such as alcoholic and nonalcoholic fatty liver disease, drug-induced liver toxicity and liver cancer. We utilize primary hepatocytes, cells culture and mouse models as well as diseased liver tissues from patients to better understand the role of these factors in liver biology and disease processes. ?The goal of the lab is to develop novel therapies for various liver diseases including hepatocellular cancer (HCC).