Director: Soledad Fernandez, PhD
Associate Director: Kevin Coombes, PhD
The Center for Biostatistics leads the Biostatistics Shared Resource (BSR) of The Ohio State University Comprehensive Cancer Center (OSUCCC – James).
For the past 25 years, the BSR has provided OSUCCC investigators a centralized resource with expertise in the biostatistical aspects of clinical, basic science and population-based research. Statistical issues are addressed at all levels of investigation: from the design of experiments to the maintenance of data quality, and from conclusions based on formal hypothesis testing to important leads discovered by data exploration. The BSR plays an essential role in ensuring that research is based on sound and appropriate statistical principles, optimal and unambiguous study designs, and analyses that robustly address scientific hypotheses while providing opportunities for discovery.
The goal of the BSR is to provide OSUCCC investigators a centralized resource for biostatistical expertise. Our primary aims are:
- To collaborate with OSUCCC investigators in planning and designing laboratory experiments, clinical trials and population-based studies.
- To conduct statistical analysis of data generated by OSUCCC pilot projects, especially complex analysis and modeling needed for microarray studies and other types of high-dimensional data.
- To identify innovative and effective statistical methods in response to specific project needs that will enhance the quality of design, interpretations and communication of results.
- To participate in all OSUCCC programs through administrative and research meetings to ensure that statistical issues are addressed.
- To provide education regarding biostatistical considerations in study design and analysis in cancer research.
- To verify and validate data quality of OSUCCC studies with the OSUCCC Clinical Trials Office, Biomedical Informatics and the Behavioral Measurement Shared Resources.